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3,4,7,8-Tetrahydro-7,7-dimethyl-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-1(6H)-one

  • CAS No. 1346674-23-4

  • Cat. No. CS-0021550
  • Purity≥97%
  • MDL No.MFCD24619432

*For research and further manufacturing use only, not for direct human use.

3,4,7,8-Tetrahydro-7,7-dimethyl-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-1(6H)-one|CS-0021550

Structure of 1346674-23-4

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General Information

  • CAS No. 1346674-23-4
  • Cat. No. CS-0021550
  • Purity ≥97%
  • MDL No. MFCD24619432
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₆N₂O
  • Molecular Weight 204.27
  • Synonym(s) 7,7-dimethyl-3,4,7,8-tetrahydro-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-1(6H)-one
  • SMILES O=C1C(N2CCN1)=CC3=C2CC(C)(C)C3

Description

This tetrahydrocyclopenta[4,5]pyrrolo[1,2-a]pyrazinone features a rigid, polycyclic core with two methyl groups at the 7-position, enhancing steric protection and metabolic stability. The saturated pyrrolopyrazinone framework supports diverse synthetic transformations, serving as a scaffold for bioactive molecule development.

Application

3,4,7,8-Tetrahydro-7,7-dimethyl-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-1(6H)-one serves as a versatile heterocyclic building block for medicinal chemistry applications. Its rigid, fused polycyclic framework provides excellent structural diversity and metabolic stability. The molecule exhibits good bench stability and functional group tolerance, facilitating downstream modifications via standard amine coupling, reductive amination, or electrophilic substitution protocols. This scaffold enables efficient access to complex nitrogen-containing frameworks relevant to drug discovery programs.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   34.03
  • LogP   1.3563
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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