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Structure of 1346229-46-6
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tert-Butyl 3-oxo-1-oxa-9-azaspiro[5.5]undecane-9-carboxylate features a rigid spirocyclic core with complementary carbonyl and amide functionalities, enabling direct integration into complex heterocyclic scaffolds. This bench-stable derivative supports efficient functionalization under mild conditions, offering precise control in medicinal chemistry campaigns targeting constrained macrocycles.
tert-Butyl 3-oxo-1-oxa-9-azaspiro[5.5]undecane-9-carboxylate serves as a versatile spirocyclic building block for the synthesis of complex heterocyclic scaffolds. Its structure features a rigid spiro core with orthogonal functional groups—namely a ketone and a tert-butyl ester—enabling selective transformations in medicinal chemistry and natural product synthesis. The compound exhibits excellent bench stability, facilitates efficient purification, and participates reliably in standard reductive amination, nucleophilic addition, and cyclization protocols.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: