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CS-W001157 4
Total: USD 88.00

CP-101537

  • CAS No. 134575-17-0

  • Cat. No. CS-W004230
  • Molecule weight198.27
  • Purity≥95%
  • MDL No.MFCD12198677

*For research and further manufacturing use only, not for direct human use.

CP-101537|CS-W004230

Structure of 134575-17-0

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General Information

  • CAS No. 134575-17-0
  • Cat. No. CS-W004230
  • Purity ≥95%
  • MDL No. MFCD12198677
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₈N₂O₂
  • Molecular Weight 198.27
  • Synonym(s) None
  • SMILES N(C(OC(C)(C)C)=O)[C@H]1[C@]2([C@@]1(CNC2)[H])[H]

Description

Inhibiting matrix metalloproteinase activity, CP-101537 (CAS 134575-17-0) suppresses extracellular matrix degradation and impedes tumor cell invasion in metastatic models.

Synthesis

  • Route1
    • Carbamic acid, [3-(phenylmethyl)-3-azabicyclo[3.1.0]hex-6-yl]-, 1,1-dimethylethyl ester, [1R-(1α,5α,6α)]-|CS-0868372
      185559-52-8
    • ~99%
    • In-stock
      CP-101537|CS-W004230
      134575-17-0

    References

    • Sun, Qin; Zhu, Ran; Foss Jr., Frank W.; Macdonald, Timothy L. Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 24 p. 6682 - 6686
  • Route2

    References

    • Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 11 p. 2773 - 2776
  • Route3
    • exo-3-[(Benzyloxy)carbonyl]-3-azabicyclo[3.1.0]hexane-6-carboxylic acid|CS-0049376
      134575-15-8
    • ~%
    • In-stock
      CP-101537|CS-W004230
      134575-17-0

    References

    • Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 11 p. 2773 - 2776

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07,GHS08
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302-H317-H318-H373
Precautionary Statements : P260-P280-P280-P302+P352-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   50.36
  • LogP   0.7289
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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