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CS-W001157 4
Total: USD 88.00

N-Boc-PEG8-alcohol

  • CAS No. 1345337-22-5

  • Cat. No. CS-0114733
  • Purity≥97%
  • MDL No.MFCD28976659

*For research and further manufacturing use only, not for direct human use.

N-Boc-PEG8-alcohol|CS-0114733

Structure of 1345337-22-5

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General Information

  • CAS No. 1345337-22-5
  • Cat. No. CS-0114733
  • Purity ≥97%
  • MDL No. MFCD28976659
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₁H₄₃NO₁₀
  • Molecular Weight 469.57
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)NCCOCCOCCOCCOCCOCCOCCOCCO

Description

N-Boc-PEG8-alcohol features a hydrophilic PEG8 chain terminating in a primary alcohol, enabling straightforward conjugation via esterification or oxidation. The N-Boc group provides temporary amine protection under mild acidic conditions, enhancing stability during synthesis and purification. This bifunctional structure facilitates modular assembly in bioconjugation, drug delivery systems, and polymer-based materials.

Application

N-Boc-PEG8-alcohol serves as a versatile, bench-stable building block for the synthesis of PEGylated compounds and bioconjugates. The terminal hydroxyl group enables straightforward derivatization via esterification, etherification, or coupling reactions, while the Boc-protected amine offers orthogonal functionality for selective modification. Its eight-ethylene glycol unit provides enhanced solubility and biocompatibility, making it ideal for applications in drug delivery systems, peptide conjugation, and surface functionalization.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362

Quality Control

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Computational Chemistry Data

  • TPSA   123.17
  • LogP   0.6196
  • H_Acceptors   10
  • H_Donors   2
  • Rotatable_Bonds   23

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