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CS-W001157 4
Total: USD 88.00

2-(Cyclopropylmethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

  • CAS No. 1344115-77-0

  • Cat. No. CS-0504702
  • Purity≥95%
  • MDL No.MFCD11052830

*For research and further manufacturing use only, not for direct human use.

2-(Cyclopropylmethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane|CS-0504702

Structure of 1344115-77-0

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General Information

  • CAS No. 1344115-77-0
  • Cat. No. CS-0504702
  • Purity ≥95%
  • MDL No. MFCD11052830
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₉BO₂
  • Molecular Weight 182.07
  • Synonym(s) Cyclopropylmethylbronic acid pinacle ester
  • SMILES CC1(C)C(C)(C)OB(CC2CC2)O1

Description

This boronate ester features a cyclopropylmethyl substituent that enhances stability and modulates reactivity in cross-coupling processes. The tetramethyl-substituted dioxaborolane ring provides excellent bench stability and moisture tolerance, enabling reliable performance under standard conditions. Ideal for Suzuki-Miyaura coupling applications requiring robust, user-friendly reagents.

Application

2-(Cyclopropylmethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane serves as a stable, bench-ready boronate reagent that facilitates Suzuki-Miyaura cross-coupling reactions under mild conditions. Its cyclopropylmethyl group imparts enhanced steric and electronic properties, improving compatibility with diverse electrophiles while maintaining high functional group tolerance and ease of purification.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H227-H315-H319-H335
Precautionary Statements : P210-P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P370+P378-P403-P405-P501

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Computational Chemistry Data

  • TPSA   18.46
  • LogP   2.4886
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   2

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