Lot numbers can be found on the outside label of a product:
Methyl 3-methylaminocrotonate
-
CAS No. 13412-12-9
- Cat. No. CS-M1728
- Purity≥98%
- MDL No.MFCD00027383
*For research and further manufacturing use only, not for direct human use.
Structure of 13412-12-9
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 13412-12-9
- Cat. No. CS-M1728
- Purity ≥98%
- MDL No. MFCD00027383
- Storage 4°C, protect from light
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₆H₁₁NO₂
- Molecular Weight 129.16
- Synonym(s) Methyl 3-(methylamino)but-2-enoate
- SMILES C/C(NC)=C\C(OC)=O
Description
Methyl 3-methylaminocrotonate is a versatile β-amino acrylate ester featuring a conjugated enone system and a tertiary amine group. This structure enables efficient Michael additions and serves as a key intermediate in synthesizing bioactive heterocycles, particularly in medicinal chemistry applications. The molecule exhibits enhanced reactivity due to the electron-donating methylamino substituent adjacent to the electrophilic β-carbon.
Application
Methyl 3-methylaminocrotonate serves as a versatile building block in synthetic organic chemistry, enabling efficient access to substituted pyrrolidines and other nitrogen-containing heterocycles via cyclization reactions. Its conjugated enamine system facilitates Michael additions and [4+2] cycloadditions, while the ester group allows for selective transformations under mild conditions. Bench-stable and amenable to purification by standard chromatography, it functions reliably in multi-step syntheses requiring functional group tolerance and predictable reactivity.
Synthesis
-
Route1
-
In-stock
105-45-3 -
74-89-5 - ~94%
-
In-stock
13412-12-9
References
-
Journal of Organic Chemistry, , vol. 75, # 17 p. 6023 - 6026
-
-
Route2
-
In-stock
17041-60-0 - ~%
-
In-stock
13412-12-9
References
-
Bulletin des Societes Chimiques Belges, , vol. 105, # 5 p. 259 - 272
-
-
Route3
-
624-90-8
-
623-43-8
- ~%
-
In-stock
13412-12-9
References
-
Bulletin des Societes Chimiques Belges, , vol. 105, # 4 p. 189 - 204
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 38.33
- LogP 0.2826
- H_Acceptors 3
- H_Donors 1
- Rotatable_Bonds 2
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- Methyl 3-methylaminocrotonate sigmaMethyl 3-methylaminocrotonate manufacturerMethyl 3-methylaminocrotonate priceMethyl 3-methylaminocrotonate structureMethyl 3-methylaminocrotonate SDSbuy Methyl 3-methylaminocrotonateMethyl 3-methylaminocrotonate supplierMethyl 3-methylaminocrotonate usesMethyl 3-methylaminocrotonate molecular weightprice of Methyl 3-methylaminocrotonateMethyl 3-methylaminocrotonate chemical name formula of Methyl 3-methylaminocrotonate