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Structure of 1340313-49-6
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This difluoromethyl-substituted thiadiazole features a reactive bromine handle at the 2-position, enabling efficient coupling in cross-coupling transformations. The electron-deficient heterocyclic core enhances stability and facilitates functionalization in synthetic workflows involving palladium catalysis or nucleophilic substitution.
2-Bromo-5-(difluoromethyl)-1,3,4-thiadiazole serves as a versatile building block for the synthesis of fluorinated heterocycles and bioactive molecules. The bromo group enables palladium-catalyzed cross-coupling reactions, while the difluoromethyl substituent imparts enhanced metabolic stability and modulates electronic properties. Its bench-stable nature and compatibility with diverse functional groups facilitate efficient incorporation into pharmaceutical scaffolds and agrochemical intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H315-H319-H332-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: