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(1-Methyl-1H-indazol-4-yl)methanamine hydrochloride

  • CAS No. 1334405-46-7

  • Cat. No. CS-0444771
  • Purity≥98%
  • MDL No.MFCD18803462

*For research and further manufacturing use only, not for direct human use.

(1-Methyl-1H-indazol-4-yl)methanamine hydrochloride|CS-0444771

Structure of 1334405-46-7

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General Information

  • CAS No. 1334405-46-7
  • Cat. No. CS-0444771
  • Purity ≥98%
  • MDL No. MFCD18803462
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₂ClN₃
  • Molecular Weight 197.66
  • Synonym(s) 4-(Aminomethyl)-1-methyl-1H-indazole hydrochloride
  • SMILES CN1C2=CC=CC(CN)=C2C=N1.Cl

Description

This bench-stable amine features a 1-methyl-1H-indazol-4-yl scaffold that delivers enhanced solubility and metabolic stability. The hydrochloride salt form ensures improved crystallinity and handling, enabling efficient integration into medicinal chemistry campaigns targeting kinase inhibitors and CNS-active compounds.

Application

(1-Methyl-1H-indazol-4-yl)methanamine hydrochloride serves as a versatile building block in medicinal chemistry, enabling efficient access to indazole-based scaffolds. Its primary amine functionality facilitates straightforward derivatization via reductive amination, amidation, or coupling reactions. The hydrochloride salt enhances solubility and stability, supporting reliable handling and purification in standard synthetic workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   43.84
  • LogP   1.4538
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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