Azido-PEG7-amine

Name: Azido-PEG7-amine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1333154-77-0
Cat. No. CS-0107278
Purity≥95%
MDL No.MFCD13185016

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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Structure of 1333154-77-0

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General Information

CAS No. 1333154-77-0
Cat. No. CS-0107278
Purity ≥95%
MDL No. MFCD13185016
Storage -20°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₆H₃₄N₄O₇
Molecular Weight 394.46
Synonym(s) None
SMILES NCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]

Description

Azido-PEG7-amine features a terminal azide group conjugated to a seven-ethylene glycol spacer terminating in a primary amine. This bifunctional linker enables efficient bioorthogonal coupling via strain-promoted or copper-catalyzed azide-alkyne cycloaddition, while the amine facilitates covalent attachment to carboxyl-containing biomolecules. The PEG spacer provides enhanced solubility and reduced non-specific binding in aqueous environments.

Application

Azido-PEG7-amine serves as a versatile bifunctional linker for bioconjugation and polymer chemistry, enabling efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) due to its terminal azide and amine groups. The seven-ethylene glycol units provide enhanced solubility and reduced non-specific binding, while the amine facilitates conjugation to carboxylated biomolecules or surfaces. Bench-stable and compatible with standard purification methods, it functions reliably in peptide modification, probe labeling, and drug delivery system construction.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

TPSA 139.39
LogP 0.3716
H_Acceptors 9
H_Donors 1
Rotatable_Bonds 23

Other Classifications

Life Science Crosslinking Agent

Life Science Linker Amino PEG

Life Science Linker PEG Azide

Building Blocks Skeleton Fatty chain compounds

Life Science ADC Related Compound Non-cleavable linker

Building Blocks Functional Group PEG

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Antibody-Drug Conjugates (ADC) Preparation Research Reagents Cross-Linkers

Chemical Biology PEGylation Monofunctional PEG and Oligoethylene Glycols

Chemical Biology PEGylation Heterobifunctional PEG and Oligoethylene Glycols

Chemical Biology PEGylation PEG Oligomers

Biochemistry Biochemicals and Reagents Antibody-Drug Conjugates (ADC) Preparation Research Reagents Cross-Linkers

Biochemistry Biochemicals and Reagents Bioconjugation PEGylation Reagents and PEG Spacers

Biochemistry Pharmaceutical Development and Drug Discovery Research Antibody-Drug Conjugates (ADC) Preparation Research Reagents Cross-Linkers

Key Words

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Azido-PEG7-amine

CAS No. 1333154-77-0

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