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Structure of 133307-08-1
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1,3-Dichloro-2-fluoro-5-iodobenzene features a highly functionalized aromatic core with orthogonal halogen handles enabling precise cross-coupling strategies. The para-iodo and ortho-fluoro substituents facilitate selective Pd-catalyzed transformations, while the dichloro pattern enhances electronic tuning for downstream derivatization in medicinal chemistry and materials synthesis.
1,3-Dichloro-2-fluoro-5-iodobenzene serves as a versatile building block in cross-coupling chemistry, enabling the construction of substituted biaryls and heterocycles under palladium-catalyzed conditions. The orthogonal reactivity of its halogen substituents—particularly iodine for facile coupling and chlorine for selective functionalization—facilitates stepwise diversification. Its bench-stable crystalline form and compatibility with standard reaction protocols make it well-suited for medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: