3,5-Difluorobenzamide

Name: 3,5-Difluorobenzamide
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 132980-99-5
Cat. No. CS-0194789
Purity≥98%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

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Description

3,5-Difluorobenzamide delivers a sterically unhindered aromatic scaffold with electron-withdrawing fluorine substituents at the meta positions. This configuration enhances metabolic stability and modulates electronic properties for use in medicinal chemistry. The amide functionality enables direct incorporation into peptide-like systems or coupling reactions under standard conditions.

Application

3,5-Difluorobenzamide serves as a versatile building block in medicinal chemistry, enabling the construction of fluorinated aromatic scaffolds prevalent in pharmaceuticals. Its stability under standard reaction conditions and compatibility with diverse coupling protocols facilitate efficient incorporation into target molecules. The ortho-difluoro substitution pattern enhances metabolic stability and modulates electronic properties, offering predictable reactivity in amide bond formation and electrophilic substitution processes.

General Information

CAS No. 132980-99-5
Cat. No. CS-0194789
Purity ≥98%
MDL No. None
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₅F₂NO
Molecular Weight 157.12
Synonym(s) Difluorobenzamide6
SMILES FC1=CC(F)=CC(C(N)=O)=C1

Computational Chemistry Data

TPSA 43.09
LogP 1.0637
H_Acceptors 1
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Other Classifications

Building Blocks Functional Group Amide

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

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3,5-Difluorobenzamide

CAS No. 132980-99-5

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