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CS-W001157 4
Total: USD 88.00

(S)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)-1-propylamine Duloxetine Impurity

  • CAS No. 132335-44-5

  • Cat. No. CS-0213950
  • Purity≥97%
  • MDL No.MFCD07782107

*For research and further manufacturing use only, not for direct human use.

(S)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)-1-propylamine Duloxetine Impurity|CS-0213950

Structure of 132335-44-5

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General Information

  • CAS No. 132335-44-5
  • Cat. No. CS-0213950
  • Purity ≥97%
  • MDL No. MFCD07782107
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₅NOS
  • Molecular Weight 185.29
  • Synonym(s) S)-(-)-N,N-dimethyl-3-hydroxy-3-(2-thienyl)-propanamine
  • SMILES [C@@H](CCN(C)C)(O)C1=CC=CS1

Synthesis

  • Route1
    • 3-(Dimethylamino)-1-(thiophen-2-yl)propan-1-one|CS-0122596
      13196-35-5
    • ~81%
    • (S)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)-1-propylamine Duloxetine Impurity|CS-0213950
      132335-44-5

    References

    • Mitsubishi Rayon Co., Ltd. Patent: EP1506965 A1, 2005 ; Location in patent: Page/Page column 35 ;
  • Route2
    • 3-(Dimethylamino)-1-(thiophen-2-yl)propan-1-one hydrochloride Duloxetine Impurity|CS-0228934
      5424-47-5
    • ~%
    • (S)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)-1-propylamine Duloxetine Impurity|CS-0213950
      132335-44-5

    References

    • US2005/197503 A1, ; Page/Page column 4 ;
  • Route3

    References

    • Lonza AG Patent: WO2004/31168 A2, 2004 ; Location in patent: Page 15-16 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   23.47
  • LogP   1.7332
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   4

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