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CS-W001157 4
Total: USD 88.00

4-Bromophthalaldehyde

  • CAS No. 13209-32-0

  • Cat. No. CS-0047310
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-Bromophthalaldehyde|CS-0047310

Structure of 13209-32-0

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General Information

  • CAS No. 13209-32-0
  • Cat. No. CS-0047310
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₅BrO₂
  • Molecular Weight 213.03
  • Synonym(s) 4-Brom-phthalaldehyd
  • SMILES O=CC1=CC(Br)=CC=C1C=O

Description

4-Bromophthalaldehyde features a brominated aromatic ring paired with two reactive aldehyde groups, enabling efficient coupling in heterocyclic synthesis. This electron-deficient di-aldehyde integrates readily into complex scaffolds under mild conditions, offering enhanced regioselectivity in transition-metal-catalyzed transformations.

Application

4-Bromophthalaldehyde serves as a versatile building block in synthetic organic chemistry, enabling efficient construction of heterocyclic scaffolds and functionalized aromatic systems. Its dual aldehyde functionality and bromine substituent provide orthogonal reactivity for coupling reactions, condensations, and transition-metal-catalyzed transformations. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for applications in medicinal chemistry and materials science.

Synthesis

  • Route1

    References

    • TRANSTECH PHARMA, INC. Patent: WO2004/14844 A2, 2004 ; Location in patent: Page 185-186 ; WO 2004/014844 A2
  • Route2
    • null|null
      4235-46-5
    • ~89%
    • In-stock
      4-Bromophthalaldehyde|CS-0047310
      13209-32-0

    References

    • Zhu, Peter C.; Roberts, Charles G.; Tran, Yvonne Patent: US2005/171201 A1, 2005 ; Location in patent: Page/Page column 12-13 ;
  • Route3
    • null|null
      583-71-1
    • ~%
    • In-stock
      4-Bromophthalaldehyde|CS-0047310
      13209-32-0

    References

    • Kerfanto,M.; Soyer,N. Bulletin de la Societe Chimique de France, 1966 , p. 2966 - 2971

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501

Quality Control

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Computational Chemistry Data

  • TPSA   34.14
  • LogP   2.0741
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   2

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