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CS-W001157 4
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(R)-2-Benzylmorpholine

  • CAS No. 131887-51-9

  • Cat. No. CS-0188089
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(R)-2-Benzylmorpholine|CS-0188089

Structure of 131887-51-9

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General Information

  • CAS No. 131887-51-9
  • Cat. No. CS-0188089
  • Purity ≥96%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₅NO
  • Molecular Weight 177.24
  • Synonym(s) (2R)-2-Benzylmorpholine
  • SMILES C1=CC=C(C=C1)C[C@@H]2CNCCO2

Description

(R)-2-Benzylmorpholine is a chiral morpholine derivative featuring a benzyl group at the 2-position, offering enhanced solubility and metabolic stability. This configuration enables selective interactions in asymmetric synthesis and medicinal chemistry applications. The stereochemistry at the 2-position imparts distinct conformational rigidity, facilitating precise molecular recognition in target engagement.

Application

(R)-2-Benzylmorpholine serves as a valuable chiral building block in medicinal chemistry, enabling the construction of bioactive heterocycles through well-established functionalization at the nitrogen and benzylic positions. Its bench-stable nature, compatibility with standard coupling reactions, and defined stereochemistry facilitate efficient synthesis of target molecules for drug discovery campaigns.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   21.26
  • LogP   1.2175
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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