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CS-W001157 4
Total: USD 88.00

2-Fluoroisonicotinaldehyde

  • CAS No. 131747-69-8

  • Cat. No. CS-W005687
  • Molecule weight125.10
  • Purity≥97%
  • MDL No.MFCD06410677

*For research and further manufacturing use only, not for direct human use.

2-Fluoroisonicotinaldehyde|CS-W005687

Structure of 131747-69-8

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General Information

  • CAS No. 131747-69-8
  • Cat. No. CS-W005687
  • Purity ≥97%
  • MDL No. MFCD06410677
  • Storage -20°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₄FNO
  • Molecular Weight 125.10
  • Synonym(s) 4-Pyridinecarboxaldehyde,2-fluoro-(9CI)
  • SMILES O=CC1=CC=NC(F)=C1

Description

2-Fluoroisonicotinaldehyde features a fluorinated pyridine ring with an aldehyde functional group positioned ortho to the fluorine. This electron-deficient heterocycle enables efficient coupling in cross-coupling reactions and serves as a key intermediate in medicinal chemistry. The molecule exhibits enhanced reactivity due to the combined electronic effects of the fluorine and carbonyl groups, making it suitable for constructing complex nitrogen-containing architectures under mild conditions.

Synthesis

  • Route1

    References

    • Ashimori; Ono; Uchida; Ohtaki; Fukaya; Watanabe; Yokoyama Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 9 p. 2446 - 2458
  • Route2
    • null|null
      79-37-8
    • In-stock
      (2-Fluoropyridin-4-yl)methanol|CS-W006245
      131747-60-9
    • ~%
    • In-stock
      2-Fluoroisonicotinaldehyde|CS-W005687
      131747-69-8

    References

    • US6358978 B1, ;
  • Route3

    References

    • Chemical and Pharmaceutical Bulletin, , vol. 38, # 9 p. 2446 - 2458

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H227-H302-H315-H319
Precautionary Statements : P210-P264-P270-P280-P302+P352-P330-P362+P364-P370+P378-P403-P501

Quality Control

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Computational Chemistry Data

  • TPSA   29.96
  • LogP   1.0332
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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