8-Chloro[1,2,4]triazolo[1,5-a]pyrazin-2-amine

Name: 8-Chloro[1,2,4]triazolo[1,5-a]pyrazin-2-amine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1314874-80-0
Cat. No. CS-0039514
Purity≥98%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

8-Chloro[1,2,4]triazolo[1,5-a]pyrazin-2-amine|CS-0039514

Structure of 1314874-80-0

Size

Price

Quantity

* Please select Quantity before adding items.

Description

8-Chloro[1,2,4]triazolo[1,5-a]pyrazin-2-amine features a fused triazolopyrazine core with a chlorine atom at the 8-position, delivering enhanced electron-withdrawing character and metabolic stability. This scaffold integrates readily into pharmaceutical intermediates, offering robust reactivity under standard coupling conditions and compatibility with diverse functional groups in medicinal chemistry applications.

Application

8-Chloro[1,2,4]triazolo[1,5-a]pyrazin-2-amine serves as a versatile heterocyclic building block in medicinal chemistry, enabling direct incorporation into kinase inhibitor scaffolds and other bioactive molecules. Its chloro group facilitates downstream cross-coupling reactions, while the fused triazolopyrazine core exhibits favorable stability and solubility for routine synthetic workflows. Functions effectively in palladium-catalyzed transformations and offers orthogonal reactivity in multi-step syntheses.

General Information

CAS No. 1314874-80-0
Cat. No. CS-0039514
Purity ≥98%
MDL No. None
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₄ClN₅
Molecular Weight 169.57
Synonym(s) None
SMILES NC1=NN2C(C(Cl)=NC=C2)=N1

Computational Chemistry Data

TPSA 69.1
LogP 0.3599
H_Acceptors 5
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Chloride

Building Blocks Skeleton Aromatic heterocycle compounds Pyrazine compounds

Building Blocks Skeleton Aromatic heterocycle compounds Triazole compounds

Key Words

1314874-80-0 sigma1314874-80-0 manufacturer1314874-80-0 price1314874-80-0 structure1314874-80-0 SDSbuy 1314874-80-01314874-80-0 supplier1314874-80-0 uses1314874-80-0 molecular weightprice of 1314874-80-01314874-80-0 chemical name formula of 1314874-80-0

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

8-Chloro[1,2,4]triazolo[1,5-a]pyrazin-2-amine

CAS No. 1314874-80-0

Recommended Products