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CS-W001157 4
Total: USD 88.00

Bis-PEG3-PFP ester

  • CAS No. 1314378-13-6

  • Cat. No. CS-0109182
  • Purity≥97%
  • MDL No.MFCD21363292

*For research and further manufacturing use only, not for direct human use.

Bis-PEG3-PFP ester|CS-0109182

Structure of 1314378-13-6

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General Information

  • CAS No. 1314378-13-6
  • Cat. No. CS-0109182
  • Purity ≥97%
  • MDL No. MFCD21363292
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₂H₁₆F₁₀O₇
  • Molecular Weight 582.34
  • Synonym(s) None
  • SMILES O=C(OC1=C(F)C(F)=C(F)C(F)=C1F)CCOCCOCCOCCC(OC2=C(F)C(F)=C(F)C(F)=C2F)=O

Description

4-(N-Maleimidomethyl)cyclohexanecarboxylic acid N-hydroxysuccinimide ester (SMCC) is a heterobifunctional cross-linking reagent incorporating an extended spacer with amine and sulfhydryl reactivity. It is typically coupled initially to molecules containing primary amine by amide bond buffered at pH 7.5 (6.5-8.5). The second coupling is specific for molecules containing free sulfhydryl by thioether linkage buffered at pH 6.8 (6.5-7.0). SMCC contains nine atom linker. An extended aliphatic spacer stabilizes the maleimide prior to coupling compared to aromatic spacers.4-(N-Maleimidomethyl)cyclohexanecarboxylic acid N-hydroxysuccinimide ester (SMCC) is useful for the preparation of enzyme immunoconjugates and hapten carrier molecule conjugates. It has been used for the coupling of a peptide sequence to an amino group.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   80.29
  • LogP   4.4186
  • H_Acceptors   7
  • H_Donors   0
  • Rotatable_Bonds   14

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