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Structure of 131190-82-4
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8-Bromo-5,6-difluoro-2-methylquinoline features a sterically accessible quinoline core with strategically positioned halogen and methyl substituents. This electron-deficient scaffold enables efficient coupling in cross-coupling reactions and serves as a key building block in medicinal chemistry for targeted bioactive molecule synthesis.
8-Bromo-5,6-difluoro-2-methylquinoline serves as a versatile building block in medicinal chemistry, enabling the construction of fluorinated heterocyclic scaffolds through palladium-catalyzed cross-coupling reactions. Its defined substitution pattern offers predictable regiochemistry and enhanced metabolic stability, while the bromo and difluoro functionalities provide orthogonal handles for further diversification. The compound exhibits good bench stability and is compatible with standard reaction conditions, facilitating efficient synthesis of complex molecular architectures.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: