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N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N-propylglycine

  • CAS No. 1310680-42-2

  • Cat. No. CS-0089994
  • Purity≥98%
  • MDL No.MFCD18328449

*For research and further manufacturing use only, not for direct human use.

N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N-propylglycine|CS-0089994

Structure of 1310680-42-2

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General Information

  • CAS No. 1310680-42-2
  • Cat. No. CS-0089994
  • Purity ≥98%
  • MDL No. MFCD18328449
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₀H₂₁NO₄
  • Molecular Weight None
  • Synonym(s) None
  • SMILES O=C(O)CN(C(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)CCC

Description

N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N-propylglycine is a bench-stable, moisture-tolerant amino acid derivative featuring a fluorenylmethoxycarbonyl (Fmoc) protecting group and a propyl-substituted nitrogen. This configuration enables efficient incorporation into peptide synthesis workflows, offering enhanced solubility and compatibility with standard coupling conditions.

Application

N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N-propylglycine serves as a versatile protected glycine equivalent in peptide synthesis, enabling efficient Nα-acylation and chain elongation. The Fmoc group provides orthogonal protection with high stability under basic conditions and facilitates straightforward removal via mild base treatment. Its propyl substitution enhances solubility and compatibility in diverse reaction media, supporting reliable coupling and purification in both manual and automated workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   66.84
  • LogP   3.7321
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   6

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