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CS-W001157 4
Total: USD 88.00

4-((tert-Butoxycarbonyl)amino)-3,3-dimethylbutanoic acid

  • CAS No. 1310680-18-2

  • Cat. No. CS-0133066
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-((tert-Butoxycarbonyl)amino)-3,3-dimethylbutanoic acid|CS-0133066

Structure of 1310680-18-2

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General Information

  • CAS No. 1310680-18-2
  • Cat. No. CS-0133066
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₂₁NO₄
  • Molecular Weight 231.29
  • Synonym(s) Boc-4-amino-3,3-dimethyl-butyric acid
  • SMILES O=C(O)CC(C)(C)CNC(OC(C)(C)C)=O

Description

This protected amino acid derivative features a tert-butoxycarbonyl (Boc) group that enables stable incorporation into peptide synthesis workflows. The sterically hindered dimethylbutanoic acid backbone enhances solubility and reduces racemization risk during coupling. Ideal for constructing complex peptide architectures under standard conditions.

Application

4-((tert-Butoxycarbonyl)amino)-3,3-dimethylbutanoic acid serves as a versatile building block in peptide synthesis and medicinal chemistry. The Boc-protected amine and terminal carboxylic acid enable sequential functionalization, while the sterically hindered tert-butyl group enhances stability and simplifies purification. It facilitates efficient coupling reactions and acts as a key intermediate in constructing complex scaffolds for API development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   75.63
  • LogP   2.012
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   4

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