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CS-W001157 4
Total: USD 88.00

Tos-PEG2-Boc

  • CAS No. 1309666-78-1

  • Cat. No. CS-0108894
  • Purity≥98%
  • MDL No.MFCD22201525

*For research and further manufacturing use only, not for direct human use.

Tos-PEG2-Boc|CS-0108894

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General Information

  • CAS No. 1309666-78-1
  • Cat. No. CS-0108894
  • Purity ≥98%
  • MDL No. MFCD22201525
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₂₄O₆S
  • Molecular Weight None
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)CCOCCOS(=O)(C1=CC=C(C)C=C1)=O

Description

Tos-PEG2-Boc features a protected amine group flanked by two ethylene glycol units, offering enhanced solubility in polar solvents. The tosyl (Tos) moiety provides stability and facilitates selective deprotection under mild conditions. This bifunctional linker enables efficient conjugation workflows in peptide synthesis and bioconjugation applications.

Application

Tos-PEG2-Boc serves as a versatile bifunctional building block for peptide and oligomer synthesis, combining the stability of a tert-butoxycarbonyl (Boc) protecting group with a tosyl (Tos) leaving group on a short PEG2 spacer. It enables efficient coupling reactions, facilitates purification via ion-exchange chromatography, and supports orthogonal deprotection strategies in complex molecule assembly.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P260-P264-P270-P271-P280-P301+P310-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   78.9
  • LogP   2.44872
  • H_Acceptors   6
  • H_Donors   0
  • Rotatable_Bonds   8

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