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CS-W001157 4
Total: USD 88.00

Ethyl trifluoropyruvate

  • CAS No. 13081-18-0

  • Cat. No. CS-W002381
  • Purity≥95%
  • MDL No.MFCD00114935

*For research and further manufacturing use only, not for direct human use.

Ethyl trifluoropyruvate|CS-W002381

Structure of 13081-18-0

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General Information

  • CAS No. 13081-18-0
  • Cat. No. CS-W002381
  • Purity ≥95%
  • MDL No. MFCD00114935
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₅F₃O₃
  • Molecular Weight 170.09
  • Synonym(s) Trifluoropyruvic Acid Ethyl Ester
  • SMILES CCOC(=O)C(=O)C(F)(F)F

Description

Ethyl 3,3,3-trifluoropyruvate is a trifluoromethylated compound. Enantioselective FriedelCrafts alkylation of simple phenols and indoles with ethyl 3,3,3-trifluoropyruvate under different reaction conditions have been reported.Ethyl 3,3,3-trifluoropyruvate may be used in the preparation of N-heteroaryl(trifluoromethyl)hydroxyalkanoic acid esters.

Synthesis

  • Route1
    • null|null
      10186-66-0
    • ~84%
    • In-stock
      Ethyl trifluoropyruvate|CS-W002381
      13081-18-0

    References

    • E. I. Du Pont de Nemours and Company Patent: US4357282 A1, 1982 ;
  • Route2
    • null|null
      10186-66-0
    • ~82%
    • null|null
      353-36-6
    • In-stock
      Ethyl trifluoropyruvate|CS-W002381
      13081-18-0

    References

    • England, David C. Journal of Organic Chemistry, 1984 , vol. 49, # 21 p. 4007 - 4008
  • Route3
    • null|null
      75-63-8
    • null|null
      95-92-1
    • ~37%
    • In-stock
      Ethyl trifluoropyruvate|CS-W002381
      13081-18-0

    References

    • Francese, C.; Tordeux, M.; Wakselman, C. Tetrahedron Letters, 1988 , vol. 29, # 9 p. 1029 - 1030

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02,GHS07
Signal Word : Warning
UN#: 3272
Class : 3
Packing Group : Ⅲ
Hazard Statements : H226-H302-H315-H319-H335
Precautionary Statements : P210-P233-P240-P241-P242-P243-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P370+P378-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   43.37
  • LogP   0.6809
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   2

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