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CS-W001157 4
Total: USD 88.00

1-Oxo-1,2-dihydroisoquinoline-6-carboxylic acid

  • CAS No. 1301214-60-7

  • Cat. No. CS-0329071
  • Purity≥98%
  • MDL No.None
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

1-Oxo-1,2-dihydroisoquinoline-6-carboxylic acid|CS-0329071

Structure of 1301214-60-7

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Description

This isoquinoline derivative features a conjugated carbonyl and carboxylic acid moiety, enabling direct integration into heterocyclic synthesis. The electron-deficient ring system supports transition metal-catalyzed couplings and facilitates functionalization at the 5- and 7-positions under mild conditions. Bench-stable and moisture-tolerant, it serves as a key scaffold for bioactive molecule development.

Application

1-Oxo-1,2-dihydroisoquinoline-6-carboxylic acid serves as a versatile scaffold for heterocyclic synthesis, enabling efficient access to isoquinoline-based medicinal intermediates. Its carboxylic acid functionality facilitates direct derivatization and coupling reactions, while the ortho-quinone-like structure supports electrophilic substitution and metal-catalyzed transformations. Bench-stable and compatible with standard purification methods, it functions reliably in multi-step synthetic sequences targeting bioactive molecules.

General Information

  • CAS No. 1301214-60-7
  • Cat. No. CS-0329071
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₇NO₃
  • Molecular Weight 189.17
  • Synonym(s) 1-Hydroxyisoquinoline-6-carboxylic acid
  • SMILES C1=C(C=C2C=CNC(=O)C2=C1)C(=O)O

Computational Chemistry Data

  • TPSA   70.16
  • LogP   1.2263
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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