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8-Bromo-6-chloro-2-methylimidazo[1,2-b]pyridazine

  • CAS No. 1298031-94-3

  • Cat. No. CS-0100938
  • Molecule weight246.49
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

8-Bromo-6-chloro-2-methylimidazo[1,2-b]pyridazine|CS-0100938

Structure of 1298031-94-3

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General Information

  • CAS No. 1298031-94-3
  • Cat. No. CS-0100938
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅BrClN₃
  • Molecular Weight 246.49
  • Synonym(s) None
  • SMILES CC1=CN2N=C(Cl)C=C(Br)C2=N1

Description

8-Bromo-6-chloro-2-methylimidazo[1,2-b]pyridazine features a sterically constrained imidazopyridazine core bearing bromo and chloro substituents at electron-deficient positions, enabling selective cross-coupling reactions. The methyl group enhances solubility and modulates reactivity, making this scaffold valuable for constructing complex heterocyclic architectures in medicinal chemistry and materials science.

Application

8-Bromo-6-chloro-2-methylimidazo[1,2-b]pyridazine serves as a versatile heterocyclic building block for medicinal chemistry and materials science applications. Its orthogonal halogenation pattern enables sequential cross-coupling reactions, while the methyl group enhances metabolic stability. The molecule exhibits excellent bench stability and facilitates efficient purification, making it well-suited for iterative synthesis workflows in API development and functionalized scaffold construction.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   30.19
  • LogP   2.45362
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   0

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