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Structure of 129768-30-5
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Ethyl 5-(trifluoromethyl)-1H-pyrazole-3-carboxylate features a trifluoromethyl group that imparts strong electron-withdrawing character, enhancing reactivity in cross-coupling and cyclization reactions. The pyrazole core provides a rigid, polar scaffold ideal for medicinal chemistry applications. This bench-stable ester integrates readily into synthetic sequences requiring nitrogen heterocycles with tunable solubility and metabolic stability.
Ethyl 5-(trifluoromethyl)-1H-pyrazole-3-carboxylate serves as a versatile building block in medicinal and process chemistry, enabling efficient construction of pyrazole-based heterocycles. The trifluoromethyl group enhances metabolic stability and lipophilicity, while the ester functionality facilitates downstream transformations including hydrolysis, reduction, and coupling reactions. Its bench-stable nature and compatibility with standard synthetic protocols make it ideal for iterative library synthesis and API intermediate development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P280-P304+P340
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Lot numbers can be found on the outside label of a product: