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Structure of 129034-38-4
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6-Iodopyridin-3-ol features a pyridin-3-ol core bearing a iodine substituent at the 6-position, delivering a reactive handle for cross-coupling transformations. The phenolic hydroxyl group enhances solubility and enables hydrogen bonding, while the electron-deficient ring facilitates nucleophilic substitution. This compound serves as a key building block in the synthesis of bioactive heterocycles and functional materials.
6-Iodopyridin-3-ol serves as a versatile building block for palladium-catalyzed cross-coupling reactions, enabling efficient access to functionalized pyridine scaffolds. Its iodide group facilitates reliable coupling with arylboranes, stannanes, and other coupling partners under standard conditions. The phenolic hydroxyl group provides orthogonal reactivity for derivatization or protection, enhancing synthetic flexibility in medicinal chemistry and materials science applications. The compound exhibits good bench stability and is readily purified by crystallization or flash chromatography.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: