Lot numbers can be found on the outside label of a product:
Boc-D-Pyroglutaminol
-
CAS No. 128811-37-0
- Cat. No. CS-0154804
- Purity≥95%
- MDL No.MFCD12911763
*For research and further manufacturing use only, not for direct human use.
Structure of 128811-37-0
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 128811-37-0
- Cat. No. CS-0154804
- Purity ≥95%
- MDL No. MFCD12911763
- Storage Store at room temperature
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₁₀H₁₇NO₄
- Molecular Weight None
- Synonym(s) tert-Butyl (2R)-2-(hydroxymethyl)-5-oxopyrrolidine-1-carboxylate USP/EP/BP
- SMILES CC(C)(C)OC(=O)N1[C@H](CCC1=O)CO
Description
Boc-D-Pyroglutaminol features a protected D-pyroglutamine scaffold with a hydroxyl group, enabling direct incorporation into peptide sequences. The Boc group ensures stability during synthesis, while the pendant alcohol facilitates conjugation or derivatization. This building block supports efficient access to cyclic peptides and bioactive analogs under standard conditions.
Application
Boc-D-Pyroglutaminol serves as a stable, bench-ready building block for the synthesis of D-pyrrolidin-2-one derivatives and cyclic peptide intermediates. Its N-Boc protection ensures compatibility with diverse coupling conditions, while the hydroxyl group enables selective derivatization or further functionalization. This chiral scaffold facilitates efficient access to bioactive heterocycles and is particularly valuable in the construction of constrained peptidomimetics and kinase inhibitor scaffolds.
Synthesis
-
Route1
-
185303-67-7 - ~%
-
In-stock
128811-37-0
References
-
Tetrahedron Letters, , vol. 35, # 23 p. 4019 - 4022
-
-
Route2
-
141293-28-9 - ~%
-
In-stock
128811-37-0
References
-
Journal of Medicinal Chemistry, , vol. 40, # 2 p. 168 - 180
-
-
Route3
-
141293-15-4
- ~%
-
In-stock
128811-37-0
References
-
Journal of Medicinal Chemistry, , vol. 40, # 2 p. 168 - 180
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H315-H319-H335
|
|
|
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 66.84
- LogP 0.9048
- H_Acceptors 4
- H_Donors 1
- Rotatable_Bonds 1
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- Boc-D-Pyroglutaminol sigmaBoc-D-Pyroglutaminol manufacturerBoc-D-Pyroglutaminol priceBoc-D-Pyroglutaminol structureBoc-D-Pyroglutaminol SDSbuy Boc-D-PyroglutaminolBoc-D-Pyroglutaminol supplierBoc-D-Pyroglutaminol usesBoc-D-Pyroglutaminol molecular weightprice of Boc-D-PyroglutaminolBoc-D-Pyroglutaminol chemical name formula of Boc-D-Pyroglutaminol