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CS-W001157 4
Total: USD 88.00

1-Boc-piperazine-3-carboxylic acid

  • CAS No. 128019-59-0

  • Cat. No. CS-D0652
  • Purity≥97%
  • MDL No.MFCD01076218
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

1-Boc-piperazine-3-carboxylic acid|CS-D0652

Structure of 128019-59-0

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Description

1-Boc-piperazine-3-carboxylic acid features a protected piperazine core with a carboxylic acid functionality, enabling direct incorporation into peptide and small-molecule scaffolds. The Boc group ensures stability during synthesis and facilitates selective deprotection under mild acidic conditions. This derivative serves as a key building block in medicinal chemistry for constructing bioactive heterocycles.

Application

1-Boc-piperazine-3-carboxylic acid serves as a versatile building block for medicinal chemistry and peptide synthesis, enabling efficient access to piperazine-containing scaffolds. The Boc group provides excellent stability and orthogonal protection, facilitating straightforward deprotection under mild acidic conditions. It functions as a key intermediate in the construction of heterocyclic APIs and bioactive molecules, demonstrating broad compatibility with standard coupling and functionalization protocols.

General Information

  • CAS No. 128019-59-0
  • Cat. No. CS-D0652
  • Purity ≥97%
  • MDL No. MFCD01076218
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₈N₂O₄
  • Molecular Weight 230.26
  • Synonym(s) N-4-Boc-2-piperazinecarboxylic acid
  • SMILES O=C(OC(C)(C)C)N1CC(NCC1)C(O)=O

Computational Chemistry Data

  • TPSA   78.87
  • LogP   0.2799
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H317-H319
Precautionary Statements : P261-P264-P272-P280-P302+P352-P362+P364-P501

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