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tert-Butyl 2,9-diazaspiro[5.5]undecane-9-carboxylate hydrochloride

  • CAS No. 1279866-58-8

  • Cat. No. CS-0037168
  • Purity≥97%
  • MDL No.MFCD22209368

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 2,9-diazaspiro[5.5]undecane-9-carboxylate hydrochloride|CS-0037168

Structure of 1279866-58-8

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General Information

  • CAS No. 1279866-58-8
  • Cat. No. CS-0037168
  • Purity ≥97%
  • MDL No. MFCD22209368
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₂₇ClN₂O₂
  • Molecular Weight 290.83
  • Synonym(s) tert butyl 2,9-diazaspiro[5.5]undecane-9-carboxylate hcl
  • SMILES CC(C)(C)OC(=O)N1CCC2(CCCNC2)CC1.Cl

Description

tert-Butyl 2,9-diazaspiro[5.5]undecane-9-carboxylate hydrochloride is a bench-stable spirocyclic diamine derivative featuring a rigid, nitrogen-rich scaffold with enhanced solubility in polar solvents. The tert-butyl ester group enables straightforward deprotection under mild acidic conditions, while the protonated amine centers facilitate salt formation and improve handling. This compound serves as a key building block for asymmetric synthesis and ligand design in catalytic systems.

Application

tert-Butyl 2,9-diazaspiro[5.5]undecane-9-carboxylate hydrochloride serves as a versatile spirocyclic scaffold for medicinal chemistry and catalytic synthesis. The protected diamine functionality enables selective derivatization and orthogonal transformations, while the tert-butyl carbamate group offers stability and facile deprotection under mild acidic conditions. Its rigid spiro architecture enhances conformational control in target molecule design, supporting efficient synthesis of complex heterocycles and API intermediates.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   41.57
  • LogP   2.8089
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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