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Potassium trifluoro(tetrahydro-2H-pyran-4-yl)borate

  • CAS No. 1279123-50-0

  • Cat. No. CS-0197797
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Potassium trifluoro(tetrahydro-2H-pyran-4-yl)borate|CS-0197797

Structure of 1279123-50-0

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General Information

  • CAS No. 1279123-50-0
  • Cat. No. CS-0197797
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₉BF₃KO
  • Molecular Weight 192.03
  • Synonym(s) Potassium tetrahydro-2H-pyran-4-trifluoroborate
  • SMILES C1COCCC1[B-](F)(F)F.[K+]

Description

Potassium trifluoro(tetrahydro-2H-pyran-4-yl)borate delivers a stable, moisture-tolerant boron source with enhanced solubility in polar solvents. This bench-stable reagent integrates readily into cross-coupling protocols, enabling efficient C–C bond formation under mild conditions. The tetrahydro-2H-pyran-4-yl group provides steric protection and improves handling without compromising reactivity.

Application

Potassium trifluoro(tetrahydro-2H-pyran-4-yl)borate serves as a stable, bench-friendly boron building block that enables selective cross-coupling reactions under mild conditions. Its tetrahydro-2H-pyran-4-yl group provides excellent functional group tolerance and facilitates efficient purification, while the trifluoroborate moiety supports reliable Suzuki-Miyaura coupling with aryl and heteroaryl halides. This reagent functions effectively in complex molecule synthesis, offering predictable reactivity and compatibility with common reaction protocols.

Safety Information

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GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302-H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501

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Computational Chemistry Data

  • TPSA   9.23
  • LogP   -0.9816
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

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