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Structure of 1279088-80-0
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This pyrazole boronate ester integrates a tetrahydropyranyl protecting group and a stable dioxaborolane moiety, enabling orthogonal functionalization in complex synthesis. It delivers reliable coupling efficiency under standard Suzuki-Miyaura conditions while maintaining excellent shelf stability and moisture tolerance.
1-(Tetrahydro-2H-pyran-2-yl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole serves as a stable, bench-ready boronate building block for Suzuki-Miyaura cross-coupling reactions. The tetrahydropyranyl (THP) group provides orthogonal protection of the pyrazole nitrogen, enabling selective functionalization and compatibility with diverse reaction conditions. Its high functional group tolerance and ease of purification make it a practical choice for constructing complex heterocyclic scaffolds in medicinal chemistry and materials synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: