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Structure of 1269233-11-5
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3-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline features a boronate ester group flanked by tetramethylcyclopentadienone rings, enabling stable coupling under Suzuki-Miyaura conditions. The chloro substituent provides orthogonal reactivity for sequential functionalization. This arylboronate integrates readily into complex scaffolds with high chemoselectivity and minimal protodeboronation.
3-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline serves as a versatile boronate building block for Suzuki-Miyaura cross-coupling reactions. The pendant chloro group enables sequential functionalization, while the sterically protected boronate moiety offers excellent shelf stability and compatibility with diverse reaction conditions. Its ortho-directed reactivity facilitates efficient construction of biaryl scaffolds and complex heterocycles in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: