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CS-W001157 4
Total: USD 88.00

rac-AntPhos

  • CAS No. 1268693-24-8

  • Cat. No. CS-0020502
  • Purity≥97%
  • MDL No.MFCD30748199

*For research and further manufacturing use only, not for direct human use.

rac-AntPhos|CS-0020502

Structure of 1268693-24-8

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General Information

  • CAS No. 1268693-24-8
  • Cat. No. CS-0020502
  • Purity ≥97%
  • MDL No. MFCD30748199
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₅H₂₃OP
  • Molecular Weight 370.42
  • Synonym(s) None
  • SMILES CC(C)(C)P1C2=C(C3=C(C=CC=C4)C4=CC5=C3C=CC=C5)C=CC=C2OC1

Description

rac-AntPhos is a bench-stable, sterically hindered phosphine ligand featuring a chiral antimony center. This configuration enhances its performance in palladium-catalyzed cross-coupling reactions, delivering improved selectivity and catalyst longevity under standard conditions.

Application

rac-AntPhos serves as a versatile, bench-stable ligand for palladium-catalyzed cross-coupling reactions, enabling efficient C–C bond formation under mild conditions. Its robust phosphine architecture provides excellent functional group tolerance and compatibility with sensitive substrates, facilitating reliable coupling in complex molecule synthesis. The racemic mixture offers practical access to asymmetric catalytic systems without requiring chiral separation, making it well-suited for high-throughput screening and process development in medicinal chemistry and materials science applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   9.23
  • LogP   6.9156
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

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