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CS-W001157 4
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5-Bromo-4-chloro-7-methyl-7H-pyrrolo[2,3-d]pyrimidine

  • CAS No. 1266343-30-9

  • Cat. No. CS-0098087
  • Purity≥95%
  • MDL No.MFCD14635647

*For research and further manufacturing use only, not for direct human use.

5-Bromo-4-chloro-7-methyl-7H-pyrrolo[2,3-d]pyrimidine|CS-0098087

Structure of 1266343-30-9

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General Information

  • CAS No. 1266343-30-9
  • Cat. No. CS-0098087
  • Purity ≥95%
  • MDL No. MFCD14635647
  • Storage -20°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅BrClN₃
  • Molecular Weight 246.49
  • Synonym(s) 5-bromo-4-chloro-7-methylpyrrolo[2,3-d]pyrimidine
  • SMILES CN1C=C(C2=C(N=CN=C21)Cl)Br

Synthesis

  • Route1

    References

    • Axten, Jeffrey M.; Medina, Jesus R.; Feng, Yanhong; Shu, Arthur; Romeril, Stuart P.; Grant, Seth W.; Li, William Hoi Hong; Heerding, Dirk A.; Minthorn, Elisabeth; Mencken, Thomas; Atkins, Charity; Liu, Qi; Rabindran, Sridhar; Kumar, Rakesh; Hong, Xuan; Goetz, Aaron; Stanley, Thomas; Taylor, J. David; Sigethy, Scott D.; Tomberlin, Ginger H.; Hassell, Annie M.; Kahler, Kirsten M.; Shewchuk, Lisa M.; Gampe, Robert T. Journal of Medicinal Chemistry, 2012 , vol. 55, # 16 p. 7193 - 7207
  • Route2
    • 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine Tofacitinib Impurity|CS-0213936
      3680-69-1
    • ~%
    • In-stock
      5-Bromo-4-chloro-7-methyl-7H-pyrrolo[2,3-d]pyrimidine|CS-0098087
      1266343-30-9

    References

    • WO2011/119663 A1, ; WO 2011/119663 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   30.71
  • LogP   2.3842
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   0

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