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CS-W001157 4
Total: USD 88.00

4-Chloro-6-methoxypyridin-3-amine

  • CAS No. 1261884-16-5

  • Cat. No. CS-0334624
  • Molecule weight158.59
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-Chloro-6-methoxypyridin-3-amine|CS-0334624

Structure of 1261884-16-5

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General Information

  • CAS No. 1261884-16-5
  • Cat. No. CS-0334624
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₇ClN₂O
  • Molecular Weight 158.59
  • Synonym(s) None
  • SMILES ClC1=CC(OC)=NC=C1N

Description

4-Chloro-6-methoxypyridin-3-amine features a pyridine core functionalized with a chloro group at C4 and a methoxy substituent at C6, creating a uniquely electron-deficient heterocyclic scaffold. This arrangement enables selective coupling reactions in medicinal chemistry, particularly in the synthesis of kinase inhibitors and antiviral agents. The compound exhibits bench-stable handling under standard conditions and integrates efficiently into diverse reaction cascades.

Application

4-Chloro-6-methoxypyridin-3-amine serves as a versatile building block in medicinal chemistry, enabling efficient construction of pyridine-based scaffolds. The chloro group facilitates nucleophilic substitution reactions, while the methoxy and amine functionalities provide orthogonal handles for further functionalization. Its bench-stable nature and compatibility with standard coupling protocols make it well-suited for modular synthesis of bioactive molecules.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   48.14
  • LogP   1.3258
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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