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Structure of 1261874-58-1
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2-(3-Fluoro-4-iodophenyl)acetic acid features a fluorinated aryl moiety paired with a reactive iodine handle, enabling efficient cross-coupling transformations. The carboxylic acid group provides polarity and synthetic versatility, while the ortho-fluorine enhances electronic modulation. This structure supports direct functionalization in biaryl synthesis and medicinal chemistry applications.
2-(3-Fluoro-4-iodophenyl)acetic acid serves as a versatile building block for palladium-catalyzed cross-coupling reactions, enabling efficient construction of biaryl and heteroaryl scaffolds. The iodine functionality provides high reactivity in Suzuki, Stille, and Negishi couplings, while the carboxylic acid group offers direct handle for derivatization or salt formation. Bench-stable and readily purified by recrystallization, it functions reliably in medicinal chemistry campaigns and API intermediate synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: