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CS-W001157 4
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Methyl 4-chloro-3-methylpicolinate

  • CAS No. 1260764-76-8

  • Cat. No. CS-W018905
  • Purity≥95%
  • MDL No.MFCD09839160

*For research and further manufacturing use only, not for direct human use.

Methyl 4-chloro-3-methylpicolinate|CS-W018905

Structure of 1260764-76-8

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General Information

  • CAS No. 1260764-76-8
  • Cat. No. CS-W018905
  • Purity ≥95%
  • MDL No. MFCD09839160
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₈ClNO₂
  • Molecular Weight 185.61
  • Synonym(s) 2-Pyridinecarboxylic acid, 4-chloro-3-methyl-, methyl ester
  • SMILES O=C(OC)C1=NC=CC(Cl)=C1C

Description

Methyl 4-chloro-3-methylpicolinate is a bench-stable, electron-deficient heterocyclic ester featuring a chlorinated pyridine core. This compound integrates readily into synthetic sequences requiring regioselective functionalization, particularly in the construction of bioactive heterocycles and pharmaceutical intermediates.

Application

Methyl 4-chloro-3-methylpicolinate serves as a versatile building block in medicinal chemistry and synthetic organic chemistry, enabling efficient construction of substituted pyridine scaffolds. The chloro group facilitates palladium-catalyzed cross-coupling reactions, while the ester functionality supports selective transformations under mild conditions. Its bench-stable nature and compatibility with diverse functional groups make it ideal for multi-step synthesis workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   39.19
  • LogP   1.83002
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   1

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