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Structure of 126069-70-3
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5,6,7,8-Tetrahydro-2-(trifluoromethyl)imidazo[1,2-a]pyrazine is a heterocyclic scaffold featuring a trifluoromethyl group that imparts enhanced metabolic stability and lipophilicity. This electron-deficient core integrates readily into medicinal chemistry campaigns targeting kinase inhibitors and CNS-active compounds. The saturated imidazopyrazine framework ensures improved solubility and reduced aromaticity compared to fully conjugated analogs.
5,6,7,8-Tetrahydro-2-(trifluoromethyl)imidazo[1,2-a]pyrazine serves as a versatile heterocyclic building block in medicinal chemistry, enabling access to bioactive scaffolds through standard functionalization protocols. Its trifluoromethyl group enhances metabolic stability and lipophilicity, while the saturated imidazopyrazine core provides a rigid, electron-deficient platform for transition metal-catalyzed couplings and nucleophilic substitutions. The compound exhibits excellent bench stability and compatibility with common purification methods, facilitating integration into multi-step syntheses of pharmaceutical candidates.
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GHS Pictogram :
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GHS No : GHS05,GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H318
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Precautionary Statements : P264-P270-P280-P330-P405-P501
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Lot numbers can be found on the outside label of a product: