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7-Bromo-6-fluoro-2,3-dihydro-1H-inden-1-one

  • CAS No. 1260011-83-3

  • Cat. No. CS-0101618
  • Purity≥98%
  • MDL No.MFCD18208172

*For research and further manufacturing use only, not for direct human use.

7-Bromo-6-fluoro-2,3-dihydro-1H-inden-1-one|CS-0101618

Structure of 1260011-83-3

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General Information

  • CAS No. 1260011-83-3
  • Cat. No. CS-0101618
  • Purity ≥98%
  • MDL No. MFCD18208172
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₆BrFO
  • Molecular Weight 229.05
  • Synonym(s) 7-BROMO-6-FLUORO-1-INDANONE
  • SMILES O=C1CCC2=C1C(Br)=C(C=C2)F

Description

7-Bromo-6-fluoro-2,3-dihydro-1H-inden-1-one features a rigid, electron-deficient indenone core with orthogonal halogen substituents enabling selective functionalization. This bench-stable ketone integrates readily into transition-metal-catalyzed coupling cascades and serves as a key scaffold for bioactive heterocycle synthesis.

Application

7-Bromo-6-fluoro-2,3-dihydro-1H-inden-1-one serves as a versatile building block in medicinal chemistry, enabling efficient construction of bioactive heterocycles through palladium-catalyzed cross-coupling and nucleophilic substitution reactions. Its ortho-halogenated indenone scaffold offers excellent functional group tolerance and bench stability, facilitating downstream derivatization in API development workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

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Computational Chemistry Data

  • TPSA   17.07
  • LogP   2.7171
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

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