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Structure of 1257535-08-2
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This bench-stable dihydrochloride salt features a fluoropyridine core paired with a primary amine handle, enabling straightforward conjugation and metal coordination. The para-fluorine enhances electrophilicity for nucleophilic substitution, while the protonated amine ensures solubility in polar solvents. Ideal for building bioactive scaffolds and catalyst ligands under standard conditions.
(6-Fluoropyridin-2-yl)methanamine dihydrochloride serves as a versatile building block in medicinal chemistry, enabling efficient construction of fluorinated heterocyclic scaffolds. Its bench-stable dihydrochloride salt form enhances handling and solubility, facilitating direct use in amide couplings, Suzuki-Miyaura cross-couplings, and nucleophilic substitution reactions. The ortho-fluoro group provides a latent site for further functionalization, while the primary amine functions as a key synthetic handle for diversification in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: