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CS-W001157 4
Total: USD 88.00

2-Oxaspiro[3.5]nonan-7-one

  • CAS No. 1256546-74-3

  • Cat. No. CS-0044813
  • Purity≥95%
  • MDL No.MFCD22628754

*For research and further manufacturing use only, not for direct human use.

2-Oxaspiro[3.5]nonan-7-one|CS-0044813

Structure of 1256546-74-3

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General Information

  • CAS No. 1256546-74-3
  • Cat. No. CS-0044813
  • Purity ≥95%
  • MDL No. MFCD22628754
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₂O₂
  • Molecular Weight 140.18
  • Synonym(s) None
  • SMILES O=C(CC1)CCC21COC2

Description

2-Oxaspiro[3.5]nonan-7-one is a bicyclic ketone featuring a spiro-linked oxirane and cyclohexanone ring system. This scaffold exhibits enhanced stability and controlled reactivity, enabling selective transformations in complex molecular architectures. The strained spirocyclic core facilitates efficient ring-opening reactions under mild conditions, making it valuable for synthetic route design in medicinal chemistry and natural product synthesis.

Application

2-Oxaspiro[3.5]nonan-7-one serves as a versatile bicyclic scaffold for medicinal chemistry and natural product synthesis, offering a rigid, three-dimensional framework with defined stereochemistry. Its spirocyclic structure features a ketone at C7 and an oxygen atom at the bridgehead, enabling selective functionalization at the carbonyl and adjacent positions. The compound exhibits excellent bench stability and facilitates efficient access to complex heterocycles via standard transformations such as nucleophilic addition, reduction, and ring-opening reactions, making it a reliable building block in multi-step synthetic sequences.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   26.3
  • LogP   1.1461
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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