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Structure of 1256359-99-5
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Tert-butyl 5-methoxy-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-1-carboxylate delivers a boronate-functionalized indole scaffold with enhanced stability and solubility. This bench-stable reagent integrates readily into Suzuki-Miyaura coupling protocols, enabling efficient C–C bond formation under mild conditions. The tetramethyl-substituted dioxaborolane moiety ensures high functional group tolerance and minimal protodeboronation.
Tert-butyl 5-methoxy-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-1-carboxylate serves as a versatile boron-containing building block for Suzuki-Miyaura cross-coupling reactions. The indole scaffold features a methoxy group at C5 and a tert-butyl carbamate at N1, providing stability and orthogonal protection. The boronate ester enables efficient coupling with aryl, heteroaryl, and vinyl halides under mild conditions, facilitating rapid access to functionalized indole derivatives in medicinal chemistry and materials synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: