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CS-W001157 4
Total: USD 88.00

3-(Bromomethyl)-1,1-difluorocyclobutane

  • CAS No. 1252934-30-7

  • Cat. No. CS-0038314
  • Purity≥97%
  • MDL No.MFCD17170416

*For research and further manufacturing use only, not for direct human use.

3-(Bromomethyl)-1,1-difluorocyclobutane|CS-0038314

Structure of 1252934-30-7

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General Information

  • CAS No. 1252934-30-7
  • Cat. No. CS-0038314
  • Purity ≥97%
  • MDL No. MFCD17170416
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₇BrF₂
  • Molecular Weight 185.01
  • Synonym(s) 3-(Bromomethyl)-1,1-difluorocyclobutane - B10723
  • SMILES C1C(CC1(F)F)CBr

Description

This difluorocyclobutane derivative features a bromomethyl group enabling direct functionalization. The strained cyclobutane core enhances reactivity, while the fluorine atoms provide metabolic stability and modulate electronic properties. Ideal for constructing complex fluorinated scaffolds in medicinal chemistry and materials science.

Application

3-(Bromomethyl)-1,1-difluorocyclobutane serves as a versatile difluorocyclobutane-based building block for medicinal chemistry and agrochemical synthesis. The bromomethyl group enables facile nucleophilic substitution and transition-metal-catalyzed coupling reactions, while the 1,1-difluoro substituent imparts enhanced metabolic stability and modulates lipophilicity. Its bench-stable nature and compatibility with diverse functional groups facilitate efficient incorporation into complex molecular architectures.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   0
  • LogP   2.4266
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   1

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