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tert-Butyl 8-oxo-2,7-diazaspiro[4.4]nonane-2-carboxylate

  • CAS No. 1251009-03-6

  • Cat. No. CS-0038185
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 8-oxo-2,7-diazaspiro[4.4]nonane-2-carboxylate|CS-0038185

Structure of 1251009-03-6

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General Information

  • CAS No. 1251009-03-6
  • Cat. No. CS-0038185
  • Purity ≥96%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₂₀N₂O₃
  • Molecular Weight 240.30
  • Synonym(s) tert-butyl 8-oxo-2,7-diazaspiro[4.4]noane-2-carboxylate
  • SMILES CC(C)(C)OC(=O)N1CCC2(CC(=O)NC2)C1

Description

tert-Butyl 8-oxo-2,7-diazaspiro[4.4]nonane-2-carboxylate features a rigid spirocyclic core with strategically positioned carbonyl and amine functionalities, enabling precise integration into complex heterocyclic scaffolds. This bench-stable, moisture-tolerant building block facilitates efficient access to bioactive nitrogen-containing frameworks through modular transformations.

Application

tert-Butyl 8-oxo-2,7-diazaspiro[4.4]nonane-2-carboxylate serves as a versatile spirocyclic building block for the synthesis of complex nitrogen-containing heterocycles. Its oxo and carbamate functionalities enable selective transformations in medicinal chemistry workflows, including reductive amination and nucleophilic addition. The tert-butyl ester offers bench stability and facile deprotection under mild acidic conditions, supporting efficient purification and scalability in multi-step syntheses.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   58.64
  • LogP   1.1335
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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