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Structure of 1246552-20-4
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This tetrahydroisoquinoline derivative features a protonated amine moiety enhancing solubility and stability under standard conditions. The saturated ring system imparts conformational rigidity, while the primary amine enables direct functionalization in synthetic sequences. This hydrochloride salt serves as a key intermediate in alkaloid synthesis and medicinal chemistry campaigns requiring a basic nitrogen scaffold with defined stereochemistry.
5,6,7,8-Tetrahydroisoquinolin-5-amine hydrochloride serves as a versatile building block in medicinal chemistry, enabling efficient access to isoquinoline-based scaffolds. Its amine functionality facilitates straightforward derivatization via alkylation, acylation, and reductive amination, while the hydrochloride salt ensures excellent bench stability and ease of handling. This compound functions effectively in standard coupling reactions and supports the synthesis of bioactive molecules requiring nitrogen-rich heterocyclic cores.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: