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Structure of 1245649-92-6
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5-Bromo-6-methoxypyrazin-2-amine features a pyrazine core functionalized with bromo and methoxy groups, enabling efficient coupling in cross-coupling reactions. The electron-deficient ring facilitates palladium-catalyzed transformations, while the methoxy substituent enhances solubility and stability under standard conditions. This scaffold serves as a key building block in medicinal chemistry and materials science.
5-Bromo-6-methoxypyrazin-2-amine serves as a versatile building block in medicinal chemistry, enabling efficient construction of pyrazine-based heterocycles through palladium-catalyzed cross-coupling reactions. Its bromine and amine functionalities offer orthogonal reactivity for sequential derivatization, while the methoxy group enhances solubility and modulates electronic properties. Bench-stable and readily purified by column chromatography, it functions reliably in standard synthetic workflows targeting kinase inhibitors and other bioactive scaffolds.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: