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Structure of 1244761-65-6
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2-Cyclopropylnicotinic acid features a cyclopropyl group at the 2-position of the nicotinic acid scaffold, imparting enhanced lipophilicity and metabolic stability. This structural motif enables direct incorporation into bioactive molecules, particularly in medicinal chemistry campaigns targeting kinase inhibitors and CNS-active compounds. The acid’s bench-stable nature facilitates handling under standard conditions.
2-Cyclopropylnicotinic acid serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard coupling and functionalization reactions. Its cyclopropyl substituent imparts enhanced metabolic stability and modulates electronic properties, while the carboxylic acid group facilitates direct amidation, esterification, or derivatization. The compound exhibits good bench stability and compatibility with diverse reaction conditions, making it well-suited for iterative synthesis workflows in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H332
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
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Lot numbers can be found on the outside label of a product: