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Structure of 1242336-80-6
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5-Amino-2-bromoisonicotinic acid features a brominated pyridine core with complementary amino and carboxylic acid functionalities. This combination enables direct coupling in peptide synthesis and facilitates downstream derivatization in medicinal chemistry. The molecule exhibits enhanced solubility in polar solvents and maintains stability under standard bench conditions, simplifying handling in multi-step transformations.
5-Amino-2-bromoisonicotinic acid serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through palladium-catalyzed cross-coupling and electrophilic substitution reactions. Its amino and bromo groups offer orthogonal functionalization potential, while the carboxylic acid facilitates derivatization via amide or ester formation. The compound exhibits good bench stability and is compatible with standard purification methods, making it well-suited for iterative synthesis campaigns targeting kinase inhibitors and other pharmaceutical scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: