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(S)-tert-Butyl 2-phenylpiperazine-1-carboxylate

  • CAS No. 1240583-48-5

  • Cat. No. CS-0060959
  • Purity≥97%
  • MDL No.MFCD08685943

*For research and further manufacturing use only, not for direct human use.

(S)-tert-Butyl 2-phenylpiperazine-1-carboxylate|CS-0060959

Structure of 1240583-48-5

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General Information

  • CAS No. 1240583-48-5
  • Cat. No. CS-0060959
  • Purity ≥97%
  • MDL No. MFCD08685943
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₂₂N₂O₂
  • Molecular Weight None
  • Synonym(s) S-1-Boc-2-phenylpiperazine
  • SMILES CC(C)(C)OC(=O)N1CCNC[C@@H]1C2=CC=CC=C2

Description

(S)-tert-Butyl 2-phenylpiperazine-1-carboxylate is a chiral piperazine derivative featuring a bench-stable tert-butyl ester and a phenyl-substituted nitrogen framework. This configuration enables selective incorporation into complex heterocycles, offering enhanced stereochemical control in medicinal chemistry applications.

Application

(S)-tert-Butyl 2-phenylpiperazine-1-carboxylate serves as a stereochemically defined building block for the synthesis of bioactive piperazine derivatives. Its tert-butyl carbamate group enables facile deprotection under mild acidic conditions, while the phenylpiperazine core provides a versatile scaffold for medicinal chemistry applications. The compound exhibits excellent bench stability and compatibility with standard coupling reactions, facilitating efficient access to complex heterocyclic architectures in drug discovery workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   41.57
  • LogP   2.568
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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