(2S,5S)-tert-Butyl 2,5-dimethylpiperazine-1-carboxylate

Name: (2S,5S)-tert-Butyl 2,5-dimethylpiperazine-1-carboxylate
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1238951-37-5
Cat. No. CS-W021077
Purity≥96%
MDL No.MFCD08686668

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

(2S,5S)-tert-Butyl 2,5-dimethylpiperazine-1-carboxylate|CS-W021077

Structure of 1238951-37-5

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 1238951-37-5
Cat. No. CS-W021077
Purity ≥96%
MDL No. MFCD08686668
Storage RT, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₁H₂₂N₂O₂
Molecular Weight 214.31
Synonym(s) (2S,5S)-2,5-DIMETHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
SMILES C[C@H]1CN([C@@H](C)CN1)C(=O)OC(C)(C)C

Description

This chiral piperazine derivative features a tert-butyl ester group at the 1-position and methyl substituents at the 2- and 5-positions, enabling stereocontrolled synthesis. The sterically encumbered tert-butyl moiety enhances stability and facilitates selective deprotection under mild conditions. This scaffold integrates readily into complex molecular architectures requiring defined spatial orientation and robust functional group tolerance.

Application

(2S,5S)-tert-Butyl 2,5-dimethylpiperazine-1-carboxylate serves as a chiral piperazine scaffold for medicinal chemistry applications, offering defined stereochemistry and enhanced metabolic stability. The tert-butyl ester group provides bench stability and facilitates straightforward deprotection under mild acidic conditions. It functions as a versatile building block in the synthesis of bioactive molecules, particularly those requiring rigid, functionalized heterocyclic cores with predictable conformational behavior.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 41.57
LogP 1.6037
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 0

Other Classifications

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Building Blocks Skeleton Aliphatic heterocycle compounds Piperazine compounds

Key Words

1238951-37-5 sigma1238951-37-5 manufacturer1238951-37-5 price1238951-37-5 structure1238951-37-5 SDSbuy 1238951-37-51238951-37-5 supplier1238951-37-5 uses1238951-37-5 molecular weightprice of 1238951-37-51238951-37-5 chemical name formula of 1238951-37-5

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

(2S,5S)-tert-Butyl 2,5-dimethylpiperazine-1-carboxylate

CAS No. 1238951-37-5

Recommended Products